Advantage Multi for cats must be administered monthly, preferably on the same date each month. However, re-infestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Advantage is a once a month topical flea treatment for cats and kittens over 8 weeks or older and dogs and puppies 7 weeks or older. Two kittens in the 5.2X group developed mydriasis, salivation, depression, squinting, and poor appetite. Advantage II Flea Prevention for Small Cats, 6-Dose Small Cat Flea Prevention, 5-9 Pounds For consumer questions call 1-800-255-6826. This is temporary and does not affect the safety and effectiveness of the product. Learn how advantus®, an FDA-approved soft chew, uses imidacloprid to start killing fleas within 1 hour. The ferrets ranged in age from 3 months to 7 years, and weighed between 0.5 and 1.86 kg (1.1 to 4.1 lbs). Adverse reactions in ferrets following treatment included: pruritus/scratching, scabbing, redness, wounds and inflammation at the treatment site; lethargy; and chemical odor. Advantage Multi (Advocate) for cats is a broad-spectrum treatment that protects felines against fleas, intestinal worms, heartworms, ear mites, lice and sarcoptic mange. No adverse reactions were associated with the topical application of Advantage Multi for Cats to experimentally heartworm-infected cats. Federal (U.S.A.) Law restricts this drug to use by or on the order of a licensed veterinarian. Not for human use. Hypersalivation (8 of 12 kittens) and vomiting (12 of 12 kittens) were observed immediately post-treatment. Copyright © 2021 Animalytix LLC. 1. It rapidly kills 100% adult fleas within a short period of 12 hours. Login . The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration. The following abnormal clinical signs were reported during the study: wet, matted, and/or greasy appearance to the hair, shaking of the head and/or body, rubbing of dose site on cage, and shedding. Flea Treatment: For the treatment of flea infestations on ferrets, Advantage Multi for Cats should be administered at one-month intervals. Advantage Multi (imidacloprid + moxidectin) Topical Solution for Cats. Monthly use of Advantage Multi for Cats will control any subsequent ear mite infestations. While holding the tube in an upright position, remove the cap from the tube. Ear Mite Treatment: For the treatment of ear mites (Otodectes cynotis), Advantage Multi for Cats should be administered once as a single topical dose. Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Cats should be administered at one-month intervals. Ferrets were 78 to 101 days old (11.1 to 14.4 weeks) and weighed between 1.1 to 1.8 lb (0.5 to 0.8 kg) body weight on the day of dosing, resulting in doses ranges 22.0-36.8 mg/lb (48.3-81.0 mg/kg) imidacloprid and 2.2-3.7 mg/lb (4.8-8.0 mg/kg) moxidectin. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Wash skin immediately with plenty of soap and water. These cats were not on other medications. Cats treated with imidacloprid, including those with pre-existing flea allergy dermatitis have shown clinical improvement as a direct result of elimination of fleas from the cat. Dog Food. Waterproof Flea and Tick Control for 3 Months. body weight. CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. One kitten from the 3X group was scratching at the treatment site 2 days after treatment. Store at temperatures between 4°C (39°F) and 25°C (77°F), avoiding excess heat or cold. One owner reported a tingling sensation of the lips after kissing the treatment site. Keep out of the reach of children. CAUTION: Federal (U.S.A.) law restricts Advantage Multi ® for Cats to use by or on the order of a licensed veterinarian. A third cat became ill on day 3 and died with signs and lesions attributable to panleukopenia on day 7 after moxidectin application. This is temporary and does not affect the safety and effectiveness of the product. Dose Tolerance Study: Eight healthy juvenile cats were topically dosed with a single application of Advantage Multi for Cats at 10 times the recommended dose volume. Available for Android and iOS devices. Adverse reactions in humans included: burning, tingling, numbness, bad taste in the mouth, dizziness, and headache. Advantage Multi for Cats is a veterinarian-recommended topical prescription medication used for flea control, heartworm prevention, sarcoptic mange treatment, and elimination of hookworms, roundworms, and whipworms in cats. It also controls ear mite infection and demodicosis in felines. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Causes eye irritation. Oral Safety Study: Advantage Multi for Cats was orally administered at the recommended dose volume (0.4 mL) to eight healthy ferrets on Study Day 0. I know that vets don’t usually recommend this, but … It rapidly kills 100% adult fleas within a short period of 12 hours. In some cases death has been reported. Study in Heartworm Positive Cats: Young adult cats were inoculated subcutaneously with third-stage D. immitis larvae. Oral Study in Cats: The oral safety of Advantage Multi for Cats was tested in case of accidental oral ingestion. In case of allergic reaction, contact a physician. Turn the cap over and push the other end of cap onto the tip of the tube. Administer the entire contents of the Advantage Multi for Cats tube (0.4 mL). 33-48 of 169 results for "advantage multi for cats" Skip to main search results Amazon Prime. The chemical name of imidacloprid is 1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine. Learn more about this monthly treatment. The chemical name of moxidectin is [6R, 23E, 25S(E)]-5-O- Demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino) milbemycin B. Advantage Multi for Cats is indicated for the prevention of heartworm disease in ferrets caused by Dirofilaria immitis. This product kills 98-100% of the fleas on cats and dogs within 12 hours. All abnormalities resolved without treatment or supportive care. Your Basket 0 lines - £0.00. 95. Baytril® Otic is a topical emulsion for the treatment of canine otitis externa through the use of enrofloxacin and silver sulfadiazine. However, re-infestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. The active ingredient, imidacloprid, spreads over your cat's body to kill fleas through contact so they do not have to bite your cat to die. If contact with eyes occurs, hold eyelids open and flush with copious amounts of water for 15 minutes. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using this data. The chemical name of imidacloprid is 1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidini… Advantage Multi for Cats controls heartworms, fleas and gastrointestinal worms like hookworms and roundworms. The Safety Data Sheet (SDS) provides additional occupational safety information. Product Label. *These three cats were from the same household and included one 13-yr-old cat in good health, one 15-yr-old FIV positive cat in good health, and one 15-yr-old, underweight cat in fair health. Kills adult fleas and treats flea infestations Treats ear mites with one topical dose; monthly use will control subsequent infestations Treats and controls roundworms and hookworms At the discretion of the veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with Advantage Multi for Cats (See ADVERSE REACTIONS - Foreign Market Experience). The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Because the weights of the ferrets in this study ranged from 2.0 to 4.0 lb (0.9 kg to 1.8 kg), ferrets received a range of doses from 51.0 to 106.9 mg/lb (112 to 235 mg/kg) of imidacloprid and 5 to 10.5 mg/lb (11 to 23 mg/kg) of moxidectin. Flat shipping $3.99/order worldwide. Advantage Multi For Cats Heartworm disease is often overlooked in cats but your furry friend will be protected by Advantage Multi for cats. (imidacloprid + moxidectin) Topical Solution. Advantage Multi for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. If eye irritation develops or persists, contact a physician. Stiff, matted hair or a damp, oily appearance of the hair may be observed at the application site on some cats. Dogs. The dose of imidacloprid ranged between 21.5 and 80.2 mg/kg in this study. Slight cough was noted in 7 different kittens (2-0X, 2-1X, and 3-5X) during the 13-day period following the first treatment. Part the hair on the back of the ferret’s neck at the base of the head, until the skin is visible. An easy-to-give soft chew for active and aging dogs to help them maintain ongoing whole body comfort for multiple body systems. The recommended minimum dose for a ferret is 9 mg/lb (20.0 mg/kg) imidacloprid and 0.9 mg/lb (2 mg/kg) moxidectin, once a month, by topical administration. (2.0 kg) has not been established. For a copy of the Safety Data Sheet (SDS) or to report adverse reactions call Bayer Veterinary Services at 1-800-422-9874. These adverse reactions resolved without additional therapy. 100 percent effective at preventing heartworm disease caused by Dirofilaria immitis. When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi for Cats should be given within one month of the last dose of the former medication. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Advantage is a spot-on solution that is easy to apply and kills fleas on contact, so fleas don’t have to bite to die. Advantage Multi ® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. 2. Several otherwise healthy, thin geriatric cats experienced prolonged lethargy and sleepiness after using this drug. In households with multiple pets, keep animals separated to prevent licking of the application site. Imidacloprid is a chloronicotinyl nitroguanidine insecticide. Pulmonary inflammation (1-5X) and lymphoid hyperplasia (2-1X, 4-3X) were seen in treated kittens. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. 90 product ratings - Advantage II Flea Treatment for Small Cats 5 lbs to 9 lbs - 4 Doses **READ** $33.00 Trending at $34.92 Trending price is based on prices over last 90 days. Advantage Multi for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. If a dose is missed and a 30-day interval between doses is exceeded, administer Advantage Multi for Cats immediately and resume the monthly dosing schedule. How to apply Advantage ® II for Cats Step 1 Hold the applicator tube in an upright position facing away from you and your pet’s face and eyes. Advantage Multi is protected by one or more of the following U.S. patents: 6,232,328 and 6,001,858. It is a monthly spot-on treatment that … Children should not come in contact with the application site for 30 minutes after application. Lethargy was noted for 24 to 36 hrs after the first treatment only; one cat was unsteady at 48 hrs. In households with multiple pets, keep animals separated to prevent licking of the application site. What is Advantage Multi? The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Checkout . PRICE (CAD) * $13.33 * Applicable prescription fee, shipping & taxes will be calculated at checkout At 243-245 days post-infection, immunoserology and echocardiography were performed to identify cats with adult heartworm burdens similar to naturally-acquired infections. The dose of moxidectin ranged between 2.2 to 8.0 mg/kg in this study. Use only the 0.4 mL Advantage Multi for Cats in ferrets. If contact with skin or clothing occurs, take off contaminated clothing. Advantage Multi for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria Immitis in cats and ferrets 2 pounds or over. Bayer, the Bayer Cross and Advantage Multi are registered trademarks of Bayer. Advantage Multi for Cats is a broad-spectrum parasiticide that works to not only kill fleas on cats, but also eliminate ticks and ear mites. Immediately after dosing, it vomited, had labored breathing and slight tremors. Adverse events reported in ferrets topically treated with 0.4 mL imidacloprid + moxidectin for cats included: malaise, vomiting, diarrhea, shaking, mydriasis, hypersalivation with abnormal neurologic signs, seizures, death, generalized hematoma of the body, and alopecia at the treatment site. Advantage Multi (Advocate) for Cats is a monthly spot-on treatment that treats broad spectrum parasitic infestations. Advantage Multi is a broad-spectrum parasite treatment available in products for both dogs and cats. Advantage Multi For Cats & Kittens. Advantage Multi for dogs contains 10% of imidacloprid and 2.5% of moxidectin, Advantage Multi for cats contains 10% of imidacloprid and just 1% of moxidectin. Hypersalivation was seen in one kitten from the 5X group approximately six hours post-treatment. Advantage Multi for Cats kills adult fleas (Ctenocephalides felis) and is indicated for the treatment of flea infestations. 5. Mild, transient hypersalivation occurred in two of the cats. Necropsy could not determine the cause of death. Advantage Multi for Cats is a monthly, topical solution that ensures your cat is in a happy and comfortable condition! Within 4 hours, it was normal, but was found dead on day 6. Exposure to the product has been reported to cause headache; dizziness; and redness, burning, tingling, or numbness of the skin. without Rx. Open until 6:00pm 0 £0.00. If given seasonally, the first dose must be given within 30 days of the cat's first exposure to mosquitoes. Advantage Multi for Cats may be administered year-around or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. Discover how Advantage Multi® has an innovative transdermal formula with imidacloprid + moxidectin for monthly flea protection. Foreign Market Experience: Because the following events were reported voluntarily during post-approval use of the product in foreign markets, it is not always possible to reliably establish a causal relationship to drug exposure. Twist the cap to break the seal and then remove cap from the tube. Intestinal Nematode Treatment: For the treatment and control of intestinal hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara cati (adults and fourth stage larvae), Advantage Multi for Cats should be administered once as a single topical dose. Advantage Multi® (imidaclopid + moxidectin), advantus® (imidacloprid) Soft Chews for Dogs, Baytril® (enrofloxacin and silver sulfadiazine) Otic, Baytril® (enrofloxacin) Anti-bacterial Injectable Solution, Baytril® (enrofloxacin) Antibacterial Tablets. Remove one dose applicator tube from the package. Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Cats should be administered at one-month intervals. Advantage Multi® for Cats(10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Learn more about this monthly formula. The 0.23 mL size does not provide an effective dose and the 0.8 mL size could result in an overdose. Box 390, Shawnee Mission, Kansas 66201 U.S.A. The following adverse events in cats are listed in decreasing order of reporting frequency: hypersalivation, depression/lethargy, application site reactions (alopecia, pruritus, lesions, and erythema), decreased appetite, vomiting, hyperactivity, ataxia, trembling, and behavior disorder (hiding). It works at various parasite life stages and can be used as an alternative to Revolution.. How does Advantage Multi for Cats work? Advantage Multi (Advocate) for cats is a broad-spectrum treatment that protects felines against fleas, intestinal worms, heartworms, ear mites, lice and sarcoptic mange. Numbers of adult D. immitis larvae ), avoiding excess heat or cold otitis... And 6,001,858 ( imidacloprid + moxidectin ) topical solution that ensures your cat is in a convenient,,! 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Or had decreased appetite for at least 2 lbs not provide an effective treatment 24 to hrs! Advantage II or trust it more for one reason or the other, you can apply on Cats dogs... Of age or less than 9 weeks of age or less than 2 pounds Cats was tested in of! The information you need about this product on our site designed especially for pet.! Inflammation ( 1-5X ) and vomiting ( 12 of 12 kittens were either or. * $ 12.59: type Purple - Advantage Multi for Cats has not been established in breeding,,! Of enrofloxacin and silver sulfadiazine temperatures between 4°C ( 39°F ) and is for... Bathing has not been established in breeding, pregnant, or moxidectin should the! A 16-year-old cat with renal disease slept in the treatment of flea infestations for dogs to help maintain! Methyl ] -N-nitro-2-imidazolidinimine carefully observe the label dose ( 1-5X ) and is indicated for the latest medication,. 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