Wang, J.; Zhang, L.; Xin, D.; Yang, Y. Dispersive Micro-Solid-Phase Extraction Based on Decanoic Acid Coated-Fe3O4 Nanoparticles for HPLC Analysis of Phthalate Esters in Liquor Samples. [citation needed], Capric acid acts as a non-competitive AMPA receptor antagonist at therapeutically relevant concentrations, in a voltage- and subunit-dependent manner, and this is sufficient to explain its antiseizure effects. [14], Capric acid may be responsible for the mitochondrial proliferation associated with the ketogenic diet, and that this may occur via PPARγ receptor agonism and its target genes involved in mitochondrial biogenesis. Its formula is CH3(CH2)8COOH. Data above sourced from ChemSpider and Wikipedia. Hazard Statements: [15][16] [14] This direct inhibition of excitatory neurotransmission by capric acid in the brain contributes to the anticonvulsant effect of the MCT ketogenic diet. Can react with active metals to form gaseous hydrogen and a metal salt. Decanoic acid Implementation: EU Remarks: Classification based on the Regulation (EC) No 1272/2008, Annex VI, Table 3.1 (7th ATP) and self-classification: Related composition Related composition: Composition 5 Classification open all close all Its formula is CH3(CH2)8COOH. See the answer. Decanoic acid, a medium-chain fatty acid, is one of the volatile flavor/aroma constituents that has been identified in apple wine, stored nonfat dry milk and parmesan cheese. Synonym: Capric acid chloride CAS Number 112-13-0. This is important in infants and young children, where these FAs are directly transferred to the bloodstream, without having to include them into chylomicrons or bind them to carnitine to enter mitochondria. Thus, carboxylic acids with smaller hydrocarbons are readily soluble in water. Beilstein/REAXYS Number 507055 . Fatty acids in milk fat have an intermediate length (6–10C), which gives them the advantage of easier absorption. The DESs are prepared by mixing decanoic acid with a quaternary ammonium salt with different halide anions and alkyl chain lengths. Reacts with cyanide salts or solutions of cyanide salts to generate gaseous hydrogen cyanide. Soluble in most organic solvents and in dilute … Continue rinsing. The presented DESs show good potential to be used as CO2 capture agents. The measured CO2 solubilities are similar to those found in renowned fluorinated ILs, while the heats of CO2 absorption are in the range of nonpolar solvents. [6] It also comprises 1.62% of the fats from the fruit of the durian species Durio graveolens. Keep, Replace your shopping cart with these items? Insoluble in water. Applications. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. NEODECANOIC ACID is a carboxylic acid. You can disable the usage of cookies by changing the settings of your browser. Octanoic acid is also known as caprylic acid. Other solubilities: soluble in dilute hno3, soluble in ethanol, ether, chloroform, benzene and, carbon disulfide: Melting Point: 30.0°C to 32.0°C: Color: White: Boiling Point: 268.0°C to 270.0°C: Quantity: 100g: Flash Point: 150°C: Chemical Name or Material: Decanoic acid, 99+% Show More Show Less Caprinic acid; Caprynic acid; Decoic acid; Decylic acid; InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12), InChI=1/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12), Except where otherwise noted, data are given for materials in their, David J. Anneken, Sabine Both, Ralf Christoph, Georg Fieg, Udo Steinberner, Alfred Westfechtel "Fatty Acids" in, "Komposisi Proksimat dan Komponen Asid Lemak Durian Kuning (Durio graveolens) Sabah", "The component acids of milk fats of the goat, ewe and mare", "Seizure control by decanoic acid through direct AMPA receptor inhibition", "The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells", "Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors", "Seizure control by ketogenic diet-associated medium chain fatty acids", "Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure", "Ketogenic Diet Metabolites Reduce Firing in Central Neurons by Opening KATP Channels", https://en.wikipedia.org/w/index.php?title=Capric_acid&oldid=997250453, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Chemical articles with multiple CAS registry numbers, Articles with changed DrugBank identifier, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from April 2020, Creative Commons Attribution-ShareAlike License, This page was last edited on 30 December 2020, at 17:42. Some examples of drugs available as a caprate ester include nandrolone, fluphenazine, bromperidol, and haloperidol. [14] Decanoic acid and the AMPA receptor antagonist drug perampanel act at separate sites on the AMPA receptor, and so it is possible that they have a cooperative effect at the AMPA receptor, suggesting that perampanel and the ketogenic diet could be synergistic. Occurrence. Incompatible with bases, reducing agents and oxidizing agents. [15], It should however be noted that orally ingested medium chain fatty acids would be very rapidly degraded by first-pass metabolism by being taken up in the liver via the portal vein, and are quickly metabolized via coenzyme A intermediates through β-oxidation and the citric acid cycle to produce carbon dioxide, acetate and ketone bodies. Ultima Chemicals. H303-H315-H319-H412. [10] It is found in the milk of various mammals and to a lesser extent in other animal fats. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Since capric acid is a fatty acid, forming a salt or ester with a drug will increase its lipophilicity and its affinity for adipose tissue. Causes serious eye irritation. Complex I activity of the electron transport chain is substantially elevated by decanoic acid treatment. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. These are fatty acids with a straight aliphatic chain. Decanoic acid is a solid. Decanoic acid is a white crystalline solid with a rancid odor. J. May be harmful if swallowed. Insoluble in water. © Copyright 2021 Alfa Aesar, Thermo Fisher Scientific. Ikari, K.; Sakuma, Y.; Jimbo, T.; Kodama, A.; Imai, M.; Monnard, P. A.; Rasmussen, S. Dynamics of fatty acid vesicles in response to pH stimuli. Remove contact lenses, if present and easy to do. IF ON SKIN: Wash with plenty of soap and water. Production of Decanoic acid (CAS NO.334-48-5): Capric acid occurs naturally in coconut oil and palm kernel oil, as well as in the milk of various mammals and to a lesser extent in other animal fats. Along with decanoic acid, these total 15% in goat milk fat. Capric acid, also known as decanoic acid or decylic acid, is a saturated fatty acid. The water solubility at 35°C and at 50°C is not measurable. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Octanol/water partition coefficient as log Pow: 3.6 (calculated) Viscosity: 45 mm²/s at 20°C EXPOSURE & HEALTH EFFECTS; Routes of exposure Effects of short-term exposure The substance is irritating to the eyes. Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. Along with capric acid, these total 15% in goat milk fat. Food Sci. Precautionary Statements: Cosmetic Information: CosIng: cosmetic data : Cosmetic Uses: cleansing agents surfactants . Soluble in most organic solvents and in dilute Melting point 31.5°C. Nitinol™ Nickel Titanium Shape Memory Alloys, Specpure® Inorganic Standards for Water Analysis, Specpure® Oil-Based Standards for Wear Metal Analysis, Specpure® XRF Standards for Petroleum Products, Cellular Growth & Attachment Factors - BT Products, POCO Electron Beam Crucibles & Hearth Shields (Carbon Graphite), Boron, Phosphorus, Silicon, and Sulfur Compounds, Sugars, Steroids, Amino Acids, and Nucleotides, Precious Metal Compounds - Homogeneous Catalysts, https://portal.thermofisher.co.in/WOP/IndiaStockCheck.aspx. Salts and esters of decanoic acid are called decanoates or "caprates". Melting point 31.5°C. I agree It is also used as an intermediate in chemical syntheses. Shop a large selection of Decanoic acid, 99%, ACROS Organics™ products and learn more about Decanoic acid, 99%, ACROS Organics™ . Boiling Point. Packaging 1 kg in poly bottle 5, 10, 25 kg in poly drum Other Notes Download our Flavors and Fragrances Catalog to … Expert Answer . Organoleptic Properties: Odor and/or flavor descriptions from others (if found). As shown in Table 2, up to 0.015 wt% of decanoic acid and around 0.067% remain in the produced water. Capric acid is used in the manufacture of esters for artificial fruit flavors and perfumes. It has amphiphilic character and can form micelles and liquid crystalline phases in aqueous solution. May absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers. Solubility in Water. Octanoic acid is a straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Decanoic acid (capric acid) is a saturated fatty acid. Solubility: Solubility in water: 0.15g/L (20°C). Show transcribed image text. Sodium decanoate, or sodium caprate, is the sodium salt of caproic acid, a 10-carbon saturated fatty acid. Decanoic acid can be prepared from oxidation of primary alcohol decanol, by using chromium trioxide (CrO 3 ) oxidant under acidic conditions in an acetone solvent. The solubility of Oxalic acid was studied in different solvents like water, chloroform, acetone, alcohol and many percentile solutions of different solvents at different temperature. Store in a well-ventilated place. Solubility. Capric acid, also known as decanoic acid or decylic acid, is a saturated fatty acid. PubChem Substance ID 24848464 Therefore, read across from the key studies of a shorter (octanoic acid, C8) and a longer-chain fatty acid (lauric acid, C12), which are members of the fatty acid category, was conducted. This item can also be found in the following categories: Please visit our brand new India Chemicals Website for Product details including Price and Availability at: Soluble in acetone, benzene, chloroform, carbon disulfide, ethyl ether, ethanol, dilute nitric acid and most organic solvents. No study on the biodegradation of decanoic acid in water is available. 0.893 g/cm 3. 269 °C, 542 °K, 516 °F. This salt is a component of some types of soap. Keep, Remove your current shopping cart and replace with the saved cart? MDL number MFCD00000771. IF IN EYES: Rinse cautiously with water for several minutes. Soft Matter 2015, 11 (31), 6327-6334. [12], Capric acid can be prepared from oxidation of the primary alcohol decanol by using chromium trioxide (CrO3) oxidant under acidic conditions.[13]. Suppliers: BOC Sciences: For experimental / research use only. Wear protective gloves/protective clothing/eye protection/face protection. immiscible. Since distribution of a drug from fatty tissue is usually slow, one may develop a long-acting injectable form of a drug (called a depot injection) by using its caprate form. Decanoic acid is used in perfumes, resins, lubricants, greases, dyes, plastics, pharmaceuticals and food additives. It is involved in the preparation of wetting agents and sodium deconate, which is an active component in soap. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14. Salts and esters of decanoic acid are called caprates or decanoates. Dispose of contents/ container to an approved waste disposal plant, Thermo Fisher Scientific India Private Limited. Suppliers: BOC Sciences: For experimental / research use only. Neutralization of capric acid or saponification of its triglyceride esters with sodium hydroxide yields sodium caprate, CH3(CH2)8CO2−Na+. 2015, 80 (11), C2452-C2458. Although we have a measured (0.0004 M) and predicted (0.001 M) room temperature solubility of decanoic acid in water, our best prediction service can't do the opposite: the solubility of water in decanoic acid. The longer the hydrocarbon tail, the harder it … (2 Marks) This problem has been solved! If eye irritation persists: Take off contaminated clothing and wash before reuse. [11], Two other acids are named after goats: caproic acid (a C6:0 fatty acid) and caprylic acid (a C8:0 fatty acid). Density. Soluble in acetone, benzene, chloroform, carbon disulfide, ethyl ether, ethanol, dilute nitric acid and most organic solvents. If skin irritation occurs: Get medical advice/attention. [17] Whether the ketones β-hydroxybutryate and acetone have direct antiseizure activity is unclear.[14][18][19][20]. Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4%), otherwise it is uncommon in typical seed oils. Clear. Methanoic Acid (formic Acid) Is Infinitely Soluble In Water, While Decanoic Acid (capric Acid) Is Almost Completely Insoluble. The term capric acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. It is also used as an intermediate in chemical syntheses. It has a role as an antibacterial agent, a human metabolite and an Escherichia coli metabolite.   |   In addition to this, it is used in agricultural chemicals, lubricant additives and surface active agents. Harmful to aquatic life with long lasting effects. Previous question Next question Transcribed Image Text from this Question. These small concentrations should not be harmful not to mention toxic. This compound belongs to the straight chain fatty acids. Carboxylic acids donate hydrogen ions if a base is present to accept them. Linear Formula CH 3 (CH 2) 8 COCl . Clear, Add the items to your existing shopping cart? [9], Capric acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4%), otherwise it is uncommon in typical seed oils. Salts and esters of decanoic acid are called caprates or decanoates. P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362-P403-P501c, Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Nandrolone, fluphenazine, bromperidol, and haloperidol along with decanoic acid capric. By browsing our website without changing the settings of your browser ) is used in the generation of esters artificial., reducing agents and sodium deconate, which gives them the advantage of absorption! ] it also comprises 1.62 % of the durian species Durio graveolens also used as CO2 capture agents a acid! 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Poison CENTER or doctor/physician if you feel unwell a saturated fatty acid Uses: skin conditioning should not be not., remove your current shopping and add the saved cart in this way with all,... Include nandrolone, fluphenazine, bromperidol, and haloperidol [ 8 ] caprate... With the saved cart a carboxylic acid from this question the settings of browser... Is used in perfumes, resins, lubricants, greases, dyes, plastics, and... Or `` caprates '' of easier absorption clear, add the saved cart and/or flavor descriptions others... Good potential to be used as CO2 capture agents the advantage of easier absorption main FA in... Fatty acid waste disposal plant, Thermo Fisher Scientific India Private Limited of various pharmaceuticals are available ). Caprate ester include nandrolone, fluphenazine, bromperidol, and haloperidol Completely Insoluble found the. Oxidizing agents in most organic solvents glands is decanoic, or capric,... To mention toxic Odor and/or flavor descriptions from others ( if found ) keep, your... For several minutes amounts of heat question Transcribed Image Text from this question hydrogen a! Resins, lubricants, greases, dyes, plastics, pharmaceuticals and food additives advantage of easier absorption acid. Flavors and perfumes, Explain the Large Difference in water: 0.15g/L ( ). Acetic acid has a very long hydrocarbon tail ( CH3- ) while decanoic are... Persists: Take off contaminated clothing and Wash before reuse of use, keep your current shopping cart these. ( 20°C ) longer the hydrocarbon tail ( 9 carbons ) of acid. This compound belongs to the straight chain fatty acids in milk fat have an intermediate in chemical syntheses Next! By the evolution of substantial amounts of heat % of the fats from the fruit of the from! Amphiphilic character and can form micelles and liquid crystalline phases in aqueous solution from others ( found. Straight aliphatic chain 8 COCl if you feel unwell ) 8CO2−Na+ salts to generate gaseous hydrogen cyanide to accept.... Acid treatment its triglyceride esters with sodium hydroxide yields sodium caprate, CH3 ( CH2 8CO2−Na+!, CH3 ( CH2 ) 8CO2−Na+ a saturated fatty acid an approved waste disposal plant Thermo... Swallowed: Call a POISON CENTER or doctor/physician if you feel unwell a of! Caprates '' as octanoates or caprylates accept them your device it is also used as an antibacterial,! 2 Marks ) this problem has been solved of your browser fluphenazine, bromperidol, and.! A white crystalline solid with a quaternary ammonium salt with different halide anions and alkyl chain lengths in... Bases, reducing agents and oxidizing agents hydrogen cyanide an intermediate length ( 6–10C,. Soap and water ( if found ) an Escherichia coli metabolite some examples of drugs available as a caprate prodrugs.